Solid Phase Extraction

Spark Holland BV

Temperature range: 20 to 80 °C
Capacity: 192 SPE cartridges (extendable to 960 cartridges)

The ACE™ Automatic Cartridge Exchanger combines the flexibility of off-line SPE with the performance and automation of on-line SPE. It selects a fresh cartridge as often as required and seals it against the pressure (up to 300 bar) of the LC system for on-line elution. Single-use or re-use of cartridges is possible. More info

Spark Holland BV

The Symbiosis™ Pico System offers all the basic advantages of online SPE (solid-phase extraction) like higher assay sensitivity, analysis of small sample injection volumes, no manual labor and lower costs of analysis while reducing method development time. It combines fully automated sample preparation with automated high-end HPLC. The system allows for parallel processing of automated sample preparation, analysis of up to 192 samples, and up to 6 selectable LC columns. More info

Spark Holland BV

The Symbiosis™ Pro system offers a unique solution for integrated online SPE-LC-MS automation (XLC-MS), which combines sample extraction and LC separation in one system. XLC-MS (eXtraction Liquid Chromatography) permits direct injection of raw biological samples such as plasma, serum or urine without prior filtration, centrifugation or protein precipitation. The system allows for parallel processing of automated sample preparation and analysis of up to 9'216 samples. More info

Spark Holland BV

The HPD™ was designed for accurate solvent delivery at controlled flow rates up to 300 bar. It allows for selection of up to 24 solvents or samples to mix on-line any two of the available solvents in ratios between 10 and 90%. More info

Spark Holland BV

The Symbiosis™ Fixed SPE system can be connected to any LC, UHPLC and LC-MS system. It works with the Spark 10 mm SPE cartridges or with third party SPE columns. An advanced model which uses up to 6 SPE cartridges or columns and which is able to perform direct LC injection is available. More info

Spark Holland BV

The HySphere™ cartridge range has been developed for online SPE systems and ensure optimal efficiency and reproducibility for a wide range of compounds. The size of the sorbent particles is below 10 µm (for most sorbents) compared to 40 µm in traditional SPE tubes, resulting in higher concentration of the analyte and, consequently, higher assay sensitivity. Small particles enable a higher sample loading speed. More info